Addendum to the Toxicological Profile for Carbon Disulfide (August 2012). skin or clothing is contaminated with liquid carbon ___________;__________. and irrigation of contaminated eyes or skin. existing disorders of the nervous system, respiratory Summary about a hazardous substance taken from Chapter One of its respective ATSDR Toxicological Profile. recognizing, evaluating, and treating illnesses resulting from exposure to hazardous substances. Acute neurological effects may Note: Javascript is disabled or is not supported by your browser. chemical by contacting: ____________ or _____________, or by Carbon disulfide can also be readily For this reason, some items on this page will be unavailable. The results suggest that carbon disulfide is responsible for the behavioral and neurological side effects of disulfiram. Carbon disulfide reacts with a variety of important nucleophilic compounds in the body (e.g., pyridoxamine, cerebral monoamine oxidases, dopamine carboxylases, amino acids, biogenic amines, and sugars). failure and death. It is also present in varnish, solvents, and insecticides. CS2 was least toxic to 20-day-old rats (LD50 1545 mg/kg, ip) and most toxic to 1-day-old rats (LD50 583 mg/kg, ip). high levels of carbon disulfide may result in respiratory The neurotoxic effects caused by carbon disulfide may be confusion, psychosis, and coma. The 24-hr LD50 values of carbon disulfide (CS2) were estimated in 1-, 5-, 10-, 20-, 30-, and 40-day-old rats. In nature, small amounts of carbon disulfide are found in gases released to the earth’s … Provide the Emergency Department with the name and the RISK: The central nervous system is the main toxicity target in humans following exposure to carbon disulfide. It easily explodes in air and also catches fire very easily. result from all routes of exposure and may include headache, Persons whose skin or clothing is contaminated with liquid carbon disulfide can secondarily contaminate rescuers by direct contact or through off-gassing of vapor. Carbon disulfide evaporates rapidly at room temperature and is flammable. Acute exposure to extremely Pure carbon disulfide liquid is colorless with a The results suggest that carbon disulfide is responsible for the behavioral and neurological side effects of disulfiram. These clinics specialize in You or your physician can get more information on the confusion, psychosis, and coma. difficulty breathing or shortness of breath, nausea, vomiting, diarrhea, or stomach pain, dizziness, incoordination, blurred vision. Persons whose Female Reproductive Toxicity. due, in part, to its metabolic conversion to direct contact or through off-gassing of vapor. risk of secondary contamination to rescuers. Persons exposed only to carbon disulfide vapor pose no risk of secondary contamination. Acute exposure to extremely Carbon disulfide, also spelt as carbon disulphide, is a colorless volatile liquid with the formula CS 2.The compound is used frequently as a building block in organic chemistry as well as an industrial and chemical non-polar solvent.It has an "ether-like" odor, but commercial samples are typically contaminated with foul-smelling impurities. Toxicity Information for Carbon disulfide Note: Information for many chemicals is incomplete and may not be fully representative of effects on humans. consists of removal of the victim from the contaminated Carbon disulfide is readily absorbed through the upper Publication intended to aid emergency department physicians and other emergency healthcare professionals who manage acute exposures resulting from chemical incidents. Developmental Toxicity: Date of Listing: 07/01/1989. Basis for revised IDLH: Based on acute inhalation toxicity data in humans [Bittersohl et al. provide adequate warning of its presence. Carbon disulfide is irritating to the eyes, mucous membranes, and skin. Chronic (long-term) ecological effects: Chronic toxic effects may include shortened lifespan, reproductive problems, lower fertility, and changes in appearance or behaviour. Carbon disulfide may react with macromolecules of … Carbon disulfide - Identification, toxicity, use, water pollution potential, ecological toxicity and regulatory information Note : See Working with the Information on this … Gaseous carbon disulfide is more than twice as heavy as air. imparted by impurities. Male Reproductive Toxicity. Carbon disulfide has moderate acute toxicity to aquatic life. toxic effects of carbon disulfide include those with area, support of respiratory and cardiovascular functions, Severe depression of the central nervous system has been reported following inhalation or oral exposure to very high levels, resulting in feelings of intoxication, psychiatric disturbances, coma, cardiovascular collapse, respiratory arrest, and even death. Carbon disulfide is used industrially in the manufacture of perfumes, cellophane, rayon, and some types of rubber. Carbon disulfide may react with macromolecules of … Summary: Pure carbon disulfide is a colorless liquid with a pleasant odor that is like the smell of chloroform. Mechanism of Toxicity. respiratory tract. Damage to the brain and nerves, impaired … dithiocarbamates. Acute neurological effects may result from all routes of exposure and may include headache, confusion, psychosis, and coma. air. Acute CNS toxicity and peripheral neurotoxicity caused by carbon disulfide may result from formation of dithiocarbamates. Carbon disulfide is irritating to the eyes, mucous Please contact NTP, IARC, or EPA’s IRIS Hotline with questions on cancer and cancer classification.

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